Identification of UPB1 as a tumor suppressor associated with immune infiltration in cholangiocarcinoma

Figure 3 Functional enrichment analyses and neighbor gene network of UPB1 in cholangiocarcinoma. A: GeneMANIA tool was used to show the relationships of neighbor genes of UPB1 and construct a network map; B: STRING tool was used to construct a protein-protein interaction network of UPB1; C: Gene Ontology enrichment analysis of UPB1; D: Kyoto Encyclopedia of Genes and Genomes pathway analysis of UPB1; E: Gene Set Enrichment Analysis of UPB1. BP: Biological process; CC: Cellular component; MF: Molecular function; cAMP: Cyclic adenosine monophosphate; IL: Interleukin; PPAR: Peroxisome proliferators-activated receptor; ABC: Adenosine triphosphate-binding cassette; AMPK: Adenosine 5’-monophosphate-activated protein kinase.