Nomogram integrating prognostic immune-inflammatory-nutritional score with clinicopathological parameters for predicting post-transplantation outcomes in hepatocellular carcinoma

doi:10.3748/wjg.122971

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World Journal of Gastroenterology

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1007-9327

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Retrospective Cohort Study

Copyright: ©Author(s) 2027. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Jan 7, 2027; 33(1): 122971
Published online Jan 7, 2027. doi: 10.3748/wjg.122971

Table 3 Cox regression analysis for disease-free survival in the training set

Variables	Univariate Cox regression		Multivariate Cox regression
Variables	HR (95%CI)	P value	HR (95%CI)	P value
PIIN score	3.140 (2.186-4.510)	< 0.001^a	3.007 (2.099-4.307)	< 0.001^a
Gender (male vs female)	1.707 (0.923-3.156)	0.088
Age (> 60 years vs ≤ 60 years)	1.263 (0.773-2.065)	0.351
Diabetes (yes vs no)	1.406 (0.880-2.245)	0.154
Hypertension (yes vs no)	0.876 (0.514-1.493)	0.627
HBV positive (yes vs no)	1.220 (0.717-2.075)	0.464
MELD score	1.010 (0.985-1.035)	0.448
Child-Pugh (C vs A-B)	1.350 (0.862-2.113)	0.189
AFP (> 40 ng/mL vs ≤ 40 ng/mL)	3.300 (2.043-5.329)	< 0.001^a	1.985 (1.182-3.334)	0.010^a
Tumor number	1.442 (1.268-1.638)	< 0.001^a	1.280 (1.117-1.466)	< 0.001^a
Tumor size	1.149 (1.092-1.208)	< 0.001^a	1.128 (1.064-1.196)	< 0.001^a
Differentiation (III vs I-II)	3.097 (1.944-4.935)	< 0.001^a	1.772 (1.067-2.943)	0.027^a
MVI (yes vs no)	2.679 (1.674-4.287)	< 0.001^a	1.465 (0.842-2.550)	0.177

^aP < 0.05.

PIIN: Prognostic immune-inflammatory-nutritional; HBV: Hepatitis B virus; MELD: Model for end-stage liver disease; AFP: Alpha fetoprotein; MVI: Microvascular invasion; HR: Hazard ratio; CI: Confidence interval.

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Citation: Huang JC, Wang HX, Zhao Y, Li XL, He Q, Lang R, Zhou L. Nomogram integrating prognostic immune-inflammatory-nutritional score with clinicopathological parameters for predicting post-transplantation outcomes in hepatocellular carcinoma. World J Gastroenterol 2027; 33(1): 122971
URL: https://www.wjgnet.com/1007-9327/full/v33/i1/122971.htm
DOI: https://dx.doi.org/10.3748/wjg.122971

Huang JC, Wang HX, Zhao Y, Li XL, He Q, Lang R, Zhou L. Nomogram integrating prognostic immune-inflammatory-nutritional score with clinicopathological parameters for predicting post-transplantation outcomes in hepatocellular carcinoma. World J Gastroenterol 2027; 33(1): 122971 [DOI: 10.3748/wjg.122971]

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