Nomogram integrating prognostic immune-inflammatory-nutritional score with clinicopathological parameters for predicting post-transplantation outcomes in hepatocellular carcinoma

doi:10.3748/wjg.122971

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World Journal of Gastroenterology

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1007-9327

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Retrospective Cohort Study

Copyright: ©Author(s) 2027. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Jan 7, 2027; 33(1): 122971
Published online Jan 7, 2027. doi: 10.3748/wjg.122971

Table 2 Cox regression analysis for overall survival in the training set

Variables	Univariate Cox regression		Multivariate Cox regression
Variables	HR (95%CI)	P value	HR (95%CI)	P value
PIIN score	3.287 (2.283-4.733)	< 0.001^a	3.277 (2.270-4.731)	< 0.001^a
Gender (male vs female)	1.734 (0.937-3.209)	0.080
Age (> 60 years vs ≤ 60 years)	1.225 (0.749-2.003)	0.419
Diabetes (yes vs no)	1.390 (0.870-2.222)	0.168
Hypertension (yes vs no)	0.806 (0.469-1.384)	0.434
HBV positive (yes vs no)	1.169 (0.687-1.989)	0.566
MELD score	1.007 (0.983-1.032)	0.562
Child-Pugh (C vs A-B)	1.334 (0.852-2.088)	0.208
AFP (> 40 ng/mL vs ≤ 40 ng/mL)	3.368 (2.081-5.450)	< 0.001^a	1.972 (1.164-3.339)	0.012^a
Tumor number	1.442 (1.269-1.638)	< 0.001^a	1.294 (1.132-1.480)	< 0.001^a
Tumor size	1.152 (1.095-1.213)	< 0.001^a	1.148 (1.079-1.221)	< 0.001^a
Differentiation (III vs I-II)	3.167 (1.988-5.045)	< 0.001^a	1.978 (1.201-3.256)	0.007^a
MVI (yes vs no)	2.650 (1.655-4.242)	< 0.001^a	1.412 (0.810-2.460)	0.224

^aP < 0.05.

PIIN: Prognostic immune-inflammatory-nutritional; HBV: Hepatitis B virus; MELD: Model for end-stage liver disease; AFP: Alpha fetoprotein; MVI: Microvascular invasion; HR: Hazard ratio; CI: Confidence interval.

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Citation: Huang JC, Wang HX, Zhao Y, Li XL, He Q, Lang R, Zhou L. Nomogram integrating prognostic immune-inflammatory-nutritional score with clinicopathological parameters for predicting post-transplantation outcomes in hepatocellular carcinoma. World J Gastroenterol 2027; 33(1): 122971
URL: https://www.wjgnet.com/1007-9327/full/v33/i1/122971.htm
DOI: https://dx.doi.org/10.3748/wjg.122971

Huang JC, Wang HX, Zhao Y, Li XL, He Q, Lang R, Zhou L. Nomogram integrating prognostic immune-inflammatory-nutritional score with clinicopathological parameters for predicting post-transplantation outcomes in hepatocellular carcinoma. World J Gastroenterol 2027; 33(1): 122971 [DOI: 10.3748/wjg.122971]

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