Research progress of plant-derived chemical compounds for overcoming pancreatic cancer drug resistance

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 32, Issue 9

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Review

©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Mar 7, 2026; 32(9): 115131
Published online Mar 7, 2026. doi: 10.3748/wjg.v32.i9.115131

Table 5 Summary of drug-resistance models and their applications in pancreatic cancer research

Research objective	Recommended model
High-throughput compound screening	2D cell lines or organoids
Microenvironment-mediated resistance mechanisms	Co-culture systems or PDX models
Personalized therapy validation	PDO, PDX, or organoids
Combination strategies with immunotherapy	Humanized immune system mice

2D: Two-dimensional; PDX: Patient-derived xenograft; PDO: Patient-derived organoids.

Citation: Yu JQ, Yu SJ, He YH, Xue YZ, Yu XF, Chen W, Hu LY, Fan XF, Gao ZF, Zhou HK, Liu XR, He XS, Wang XG. Research progress of plant-derived chemical compounds for overcoming pancreatic cancer drug resistance. World J Gastroenterol 2026; 32(9): 115131
URL: https://www.wjgnet.com/1007-9327/full/v32/i9/115131.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i9.115131

Yu JQ, Yu SJ, He YH, Xue YZ, Yu XF, Chen W, Hu LY, Fan XF, Gao ZF, Zhou HK, Liu XR, He XS, Wang XG. Research progress of plant-derived chemical compounds for overcoming pancreatic cancer drug resistance. World J Gastroenterol 2026; 32(9): 115131 [PMID: 41810441 DOI: 10.3748/wjg.v32.i9.115131]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.