Comparable remission and health care use in real-world inflammatory bowel disease patients initiating originator biologics vs biosimilars

doi:10.3748/wjg.v32.i9.114580

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Mar 7, 2026; 32(9): 114580
Published online Mar 7, 2026. doi: 10.3748/wjg.v32.i9.114580

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Figure 1 Kaplan-Meier curve for the time to first remission (among those without remission at baseline), stratified by originator biologic and biosimilar, Canadian IBD Research Consortium cohort, Canada, 2018-2024. The median time to clinical remission was 12.8 months [95% confidence interval (95%CI): 7.5-23.8 months] for originator users and 12.2 months (95%CI: 9.3-24.1 months) for biosimilar users. No significant difference in the time to achieve remission between biosimilar and originator users was detected.

Citation: Moura CS, Etingin A, Lukusa L, Singh H, Narula N, Targownik LE, Leung Y, Zezos P, Polewiczowska-Nowak B, Afif W, Bernatsky S. Comparable remission and health care use in real-world inflammatory bowel disease patients initiating originator biologics vs biosimilars. World J Gastroenterol 2026; 32(9): 114580
URL: https://www.wjgnet.com/1007-9327/full/v32/i9/114580.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i9.114580

Moura CS, Etingin A, Lukusa L, Singh H, Narula N, Targownik LE, Leung Y, Zezos P, Polewiczowska-Nowak B, Afif W, Bernatsky S. Comparable remission and health care use in real-world inflammatory bowel disease patients initiating originator biologics vs biosimilars. World J Gastroenterol 2026; 32(9): 114580 [PMID: 41810446 DOI: 10.3748/wjg.v32.i9.114580]

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