Perioperative serum carcinoembryonic antigen: Powerful marker for prognostic prediction and adjuvant chemotherapy decision-making in patients with stage II and III colorectal cancer

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Mar 7, 2026; 32(9): 114200
Published online Mar 7, 2026. doi: 10.3748/wjg.v32.i9.114200

Table 6 Recurrence or metastasis rates in different carcinoembryonic antigen level

Level	Recurrence or metastasis rate in training cohort (%)	Recurrence or metastasis rate in validation cohort (%)
Elevated pre-CEA	17.92	10.61
Normal pre-CEA	10.69	8.74
Elevated post-CEA	27.58	19.13
Normal post-CEA	11.04	7.75
Total	13.42	9.36

pre-CEA: Preoperative carcinoembryonic antigen; post-CEA: Postoperative carcinoembryonic antigen.

Citation: Du FQ, Liu JL, Mai LD, Han XH, Song WJ, Yang D, Zhang QJ, Zhang R, Liu YL, Tong JX. Perioperative serum carcinoembryonic antigen: Powerful marker for prognostic prediction and adjuvant chemotherapy decision-making in patients with stage II and III colorectal cancer. World J Gastroenterol 2026; 32(9): 114200
URL: https://www.wjgnet.com/1007-9327/full/v32/i9/114200.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i9.114200

Du FQ, Liu JL, Mai LD, Han XH, Song WJ, Yang D, Zhang QJ, Zhang R, Liu YL, Tong JX. Perioperative serum carcinoembryonic antigen: Powerful marker for prognostic prediction and adjuvant chemotherapy decision-making in patients with stage II and III colorectal cancer. World J Gastroenterol 2026; 32(9): 114200 [PMID: 41810442 DOI: 10.3748/wjg.v32.i9.114200]

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