Molecular mechanisms of tumor-associated macrophages in hepatocellular carcinoma development and therapy

doi:10.3748/wjg.v32.i8.115675

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 28, 2026; 32(8): 115675
Published online Feb 28, 2026. doi: 10.3748/wjg.v32.i8.115675

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Figure 2 Triggering receptor expressed on myeloid cells-1 and triggering receptor expressed on myeloid cells-2 in tumor-associated macrophages modulate the infiltration and function of cluster of differentiation 8⁺ T cells and regulatory T cells, thereby impacting hepatocellular carcinoma progression. TAMs: Tumor-associated macrophages; TREM: Triggering receptor expressed on myeloid cells; CD: Cluster of differentiation; Treg: Regulatory T cell; HCC: Hepatocellular carcinoma.

Citation: Yang M, Zhang CY. Molecular mechanisms of tumor-associated macrophages in hepatocellular carcinoma development and therapy. World J Gastroenterol 2026; 32(8): 115675
URL: https://www.wjgnet.com/1007-9327/full/v32/i8/115675.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i8.115675

Yang M, Zhang CY. Molecular mechanisms of tumor-associated macrophages in hepatocellular carcinoma development and therapy. World J Gastroenterol 2026; 32(8): 115675 [PMID: 41809883 DOI: 10.3748/wjg.v32.i8.115675]

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