Optimizing Helicobacter pylori therapy through gastroenterologist education: A prospective interventional study

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Prospective Study

World J Gastroenterol. Feb 21, 2026; 32(7): 115876
Published online Feb 21, 2026. doi: 10.3748/wjg.v32.i7.115876

Table 4 Comparison of Helicobacter pylori eradication rates before and after training according to physicians’ experience

	ITT analysis				PP analysis
	Before training	After training	χ²	P value	Before training	After training	χ²	P value
According to treatment experience
Inexperienced physicians	56.8% (155/273)	72.2% (197/273)	14.10	< 0.001	78.7% (155/197)	86.0% (197/229)	3.98	0.046
Experienced physicians	60.8% (135/222)	71.0% (159/224)	5.14	0.023	84.4% (135/160)	91.9% (159/173)	4.56	0.033
According to ITT analysis of H. pylori eradication rates before training
Physicians with eradication rates below 80%	51.4% (203/395)	68.3% (271/397)	23.45	< 0.001	78.4% (203/259)	88.3% (271/307)	10.11	0.001
Physicians with eradication rates no less than 80%	87.0% (87/100)	85.0% (85/100)	0.17	0.684	88.8% (87/98)	89.5% (85/95)	0.02	0.876
According to PP analysis of H. pylori eradication rates before training
Physicians with eradication rates below 85%	45.7% (112/245)	65.6% (162/247)	19.69	< 0.001	72.7% (112/154)	87.1% (162/186)	10.11	0.001
Physicians with eradication rates no less than 85%	71.2% (178/250)	77.6% (194/250)	2.69	0.101	87.7% (178/203)	89.8% (194/216)	0.48	0.490

H. pylori: Helicobacter pylori; ITT: Intention-to-treat; PP: Per-protocol.

Citation: Duan M, Kong QZ, Zuo XL, Yang XY, Li YY. Optimizing Helicobacter pylori therapy through gastroenterologist education: A prospective interventional study. World J Gastroenterol 2026; 32(7): 115876
URL: https://www.wjgnet.com/1007-9327/full/v32/i7/115876.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i7.115876

Duan M, Kong QZ, Zuo XL, Yang XY, Li YY. Optimizing Helicobacter pylori therapy through gastroenterologist education: A prospective interventional study. World J Gastroenterol 2026; 32(7): 115876 [PMID: 41694492 DOI: 10.3748/wjg.v32.i7.115876]

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