Optimizing Helicobacter pylori therapy through gastroenterologist education: A prospective interventional study

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Prospective Study

World J Gastroenterol. Feb 21, 2026; 32(7): 115876
Published online Feb 21, 2026. doi: 10.3748/wjg.v32.i7.115876

Table 3 Comparisons before and after training

	Group A	Group B	χ² test		Logistic regression model		Linear mixed model
	Before training	After training	χ²	P value	OR	95%CI	Effect size	95%CI	P value
H. pylori eradication rates
ITT analysis	58.59% (290/495)	71.63% (356/497)	18.58	< 0.001	1.785	1.370-2.325	0.132	0.049-0.214	0.004
PP analysis	81.23% (290/357)	88.56% (356/402)	8.01	0.005	1.788	1.191-2.684	0.079	0.018-0.139	0.012
Standardization rates of H. pylori eradication therapies	71.0% (355/500)	89.6% (448/500)	54.57	< 0.001	3.519	2.490-4.974	0.186	0.054-0.312	0.008
Patient review rate	71.4% (357/500)	80.4% (402/500)	11.07	0.001	1.643	1.225-2.204	0.090	0.031-0.149	0.005
Adverse reaction documentation rates for physicians	21.0% (103/490)	21.2% (104/491)	0.00	0.951	1.01	0.743-1.372	-0.001	-0.052-0.051	0.984

H. pylori: Helicobacter pylori; CI: Confidence interval; OR: Odds ratio; ITT: Intention-to-treat; PP: Per-protocol.

Citation: Duan M, Kong QZ, Zuo XL, Yang XY, Li YY. Optimizing Helicobacter pylori therapy through gastroenterologist education: A prospective interventional study. World J Gastroenterol 2026; 32(7): 115876
URL: https://www.wjgnet.com/1007-9327/full/v32/i7/115876.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i7.115876

Duan M, Kong QZ, Zuo XL, Yang XY, Li YY. Optimizing Helicobacter pylori therapy through gastroenterologist education: A prospective interventional study. World J Gastroenterol 2026; 32(7): 115876 [PMID: 41694492 DOI: 10.3748/wjg.v32.i7.115876]

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