Anatomical laterality of primary intestinal diffuse large B-cell lymphoma independently stratifies survival: New prognostic nomogram incorporating tumor location

Table 2 Univariable and multivariable Cox analyses of overall survival in the SEER cohort before and after propensity score matching

Analysis	Characteristics	Before propensity score matching		After propensity score matching
		HR (95%CI)	P value	HR (95%CI)	P value
Univariate analysis	Age
	< 50	Reference		Reference
	50-69	1.77 (1.47-2.13)	< 0.001	1.37 (1.03-1.80)	0.028
	70-89	4.41 (3.69-5.27)	< 0.001	3.87 (2.98-5.02)	< 0.001
	≥ 90	10.20 (7.93-13.1)	< 0.001	8.47 (5.81-12.4)	< 0.001
	Gender
	Female	Reference		Reference
	Male	0.95 (0.87-1.04)	0.292	0.89 (0.77-1.02)	0.103
	Race
	White	Reference		Reference
	Black	0.96 (0.78-1.17)	0.670	1.02 (0.74-1.39)	0.922
	Other	0.88 (0.76-1.02)	0.100	0.69 (0.54-0.89)	0.004
	Stage
	Stage I/II	Reference		Reference
	Stage III/IV	1.48 (1.34-1.63)	< 0.001	1.59 (1.38-1.84)	< 0.001
	Laterality
	Right side	Reference		Reference
	Left side	1.31 (1.15-1.48)	< 0.001	1.22 (1.05-1.41)	0.008
	Radiation
	Yes	Reference		Reference
	No/unknown	0.88 (0.74-1.04)	0.124	0.98 (0.80-1.20)	0.857
	Surgery
	Yes	Reference		Reference
	No	1.19 (1.09-1.30)	< 0.001	1.14 (0.99-1.31)	0.057
	Chemotherapy
	Yes	Reference		Reference
	No/unknown	1.97 (1.80-2.17)	< 0.001	2.14 (1.86-2.46)	< 0.001
Multivariate analysis	Age
	< 50	Reference		Reference
	50-69	1.76 (1.46-2.12)	< 0.001	1.31 (0.99-1.72)	0.061
	70-89	4.14 (3.46-4.95)	< 0.001	3.29 (2.53-4.38)	< 0.001
	≥ 90	7.97 (6.15-10.31)	< 0.001	6.17 (4.18-9.12)	< 0.001
	Stage
	Stage I/II	Reference		Reference
	Stage III/IV	1.66 (1.50-1.83)	< 0.001	1.67 (1.44-1.93)	< 0.001
	Laterality
	Right side	Reference		Reference
	Left side	1.15 (1.01-1.31)	0.035	1.16 (1.01-1.35)	0.040
	Surgery
	Yes	Reference		Reference
	No	1.26 (1.15-1.39)	< 0.001	1.23 (1.06-1.42)	0.006
	Chemotherapy
	Yes	Reference		Reference
	No/unknown	1.80 (1.63-1.99)	< 0.001	1.86 (1.60-2.17)	< 0.001

HR: Hazard ratio; CI: Confidence interval.