New-onset persistent organ failure predicts adverse outcomes in patients with severe acute pancreatitis

doi:10.3748/wjg.v32.i7.114773

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 32, Issue 7

This Article

(56)

(62)

(0)

(14)

(1255)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Supplementary Materials of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Gastroenterol. Feb 21, 2026; 32(7): 114773
Published online Feb 21, 2026. doi: 10.3748/wjg.v32.i7.114773

Table 3 Predictors of in-hospital mortality among patients with severe acute pancreatitis, n (%)

Variables	Died (n = 15)	Survived (n = 136)	Univariable analysis		Multivariable analysis
Variables	Died (n = 15)	Survived (n = 136)	OR (95%CI)	P value	OR (95%CI)	P value
Age, median (IQR)	47 (39, 61)	47 (35, 61)	1.1 (0.9-1.1)	0.497
Male	8 (53.3)	68 (50)	1.1 (0.4-3.3)	0.807
BISAP score, median (IQR)	3 (3, 4)	3 (2, 3)	3.3 (1.6-6.8)	0.002^a	4.0 (1.3-12.0)	0.013^a
CTSI score, median (IQR)	8 (8, 10)	4 (4, 6)	1.7 (1.3-2.2)	< 0.001^a
IPN	12 (80.0)	40 (29.4)	9.6 (2.6-35.9)	0.001^a
OPN	4 (26.7)	4 (2.9)	12.0 (2.6-54.7)	0.001^a
MC	13 (86.7)	26 (19.1)	27.5 (5.8-129.4)	< 0.001^a	13.2 (2.1-83.5)	0.006^a
MOF on admission	10 (66.7)	30 (22.1)	7.1 (2.2-22.3)	0.001^a
OF duration > 2 weeks	12 (80.0)	34 (25)	12.0 (3.2-45.1)	< 0.001^a
NOOF	13 (86.7)	25 (18.4)	28.9 (6.1-136.1)	< 0.001^a	7.5 (1.3-42.6)	0.024^a

^aP < 0.05.

OR: Odds ratio; CI: Confidence interval; IQR: Interquartile range; BISAP: Bedside Index of Severity in Acute Pancreatitis; CTSI: Computed tomography severity index; IPN: Infected pancreatic necrosis; OPN: Open pancreatic necrosectomy; MC: Major complications; MOF: Multiple organ failure; OF: Organ failure; NOOF: New-onset organ failure.

Full Size Table

Citation: Zhang XT, Zhu H, Chen XC, Gao T, Chen M, Zhu ZH, Zhang BY, Yu WK. New-onset persistent organ failure predicts adverse outcomes in patients with severe acute pancreatitis. World J Gastroenterol 2026; 32(7): 114773
URL: https://www.wjgnet.com/1007-9327/full/v32/i7/114773.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i7.114773

Zhang XT, Zhu H, Chen XC, Gao T, Chen M, Zhu ZH, Zhang BY, Yu WK. New-onset persistent organ failure predicts adverse outcomes in patients with severe acute pancreatitis. World J Gastroenterol 2026; 32(7): 114773 [PMID: 41694487 DOI: 10.3748/wjg.v32.i7.114773]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.