New-onset persistent organ failure predicts adverse outcomes in patients with severe acute pancreatitis

Table 2 Comparison of clinical outcomes among new-onset multi-organ failure, new-onset single organ failure, and organ failure groups, n (%)

Characteristics	NOOF (n = 38)		OF (n = 113)	P value1	P value2
	NOMOF (n = 21)	NOSOF (n = 17)
ICU admission	21 (100.0)	17 (100.0)	88 (77.9)	0.002a	-
ICU LOS, median days (IQR)	45 (24, 58)	30 (13, 51)	8 (3, 13)	< 0.001a	0.347
Hospital LOS, median days (IQR)	50 (35, 62)	93 (44, 117)	29 (21, 40)	< 0.001a	0.086
Hospital care costs, thousand CNY, median (IQR)	538 (309, 690)	553 (273, 772)	83 (55, 144)	< 0.001a	0.941
OF duration, median days (IQR)	37 (21, 47)	20 (12, 30)	7 (3, 11)	< 0.001a	0.015a
MV duration, median days (IQR)	7 (2, 21)	0 (0, 6)	0 (0, 0)	< 0.001a	0.016a
Vasopressors duration, median days (IQR)	6 (3, 8)	1 (0, 9)	0 (0, 0)	< 0.001a	0.028a
RRT duration, median days (IQR)	12 (3, 18)	1 (0, 10)	0 (0, 0)	< 0.001a	0.039a
In-hospital mortality	12 (57.1)	1 (5.9)	2 (1.8)	< 0.001a	0.001a
90-day mortality	17 (81.0)	3 (17.6)	3 (2.7)	< 0.001a	< 0.01a

^aP < 0.05.

¹Group new-onset organ failure vs organ failure.

²Group new-onset multi-organ failure vs new-onset single organ failure.

NOOF: New-onset organ failure; OF: Organ failure; NOMOF: New-onset multi-organ failure; NOSOF: New-onset single organ failure; ICU: Intensive care unit; LOS: Length of stay; IQR: Interquartile range; CNY: Chinese Yuan; MV: Mechanical ventilation; RRT: Renal replacement therapy.