Gallbladder carcinoma in Brazil: Clinicopathological profile and survival outcomes from a high-volume cancer center

Table 2 Univariable and multivariable analysis for overall survival - all gallbladder cancer patients

Overall survival, variables	Univariable			Multivariable
	HR	95%CI	P value	HR	95%CI	P value
Male (vs female)	1.50	0.87-1.53	0.300	-	-	-
Age > 65 (vs < 65 years)	0.91	0.71-1.17	0.453	-	-	-
ECOG > 2 (vs 0-1)	2.78	2.18-3.56	< 0.001	1.91	1.48-2.48	< 0.000
Stage T1 (Ref)
vs T2	3.83	1.74-8.44	0.001	2.80	1.25-6.28	0.013
vs T3	8.76	4.07-18.87	< 0.001	4.38	1.94-9.89	< 0.000
vs T4	13.63	6.27-29.66	< 0.001	5.24	2.25-12.16	< 0.000
N+ (vs N0)	3.02	2.24-4.08	< 0.001	0.99	0.69-1.43	0.969
M1 (vs M0)	5.01	3.62-6.95	< 0.001	2.76	1.88-4.05	< 0.000
Non-IGBC (vs IGBC)	2.24	1.76-2.85	< 0.001	1.35	1.01-1.80	0.041

HR: Hazard ratio; CI: Confidence interval; ECOG: Eastern Cooperative Oncology Group; IGBC: Incidental gallbladder cancer.