Efficacy and safety of sequential hyperthermic intraperitoneal chemotherapy following surgery for pathological T staging 4 gastric cancer

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Gastroenterol. Feb 14, 2026; 32(6): 115556
Published online Feb 14, 2026. doi: 10.3748/wjg.v32.i6.115556

Table 3 Adverse treatment reaction, n (%)

	Before PSM				After PSM
	HIPEC + AC group	AC group	χ²	P value	HIPEC + AC group	AC group	χ²	P value
Myelosuppression			0.912	0.339			1.006	0.316
Yes	27 (28.13)	44 (34.11)			24 (30.00)	30 (37.50)
No	69 (71.88)	85 (65.89)			56 (70.00)	50 (62.50)
Liver function abnormalities			0.047	0.829			0.000	1.000
Yes	11 (11.46)	16 (12.40)			10 (12.50)	10 (12.50)
No	85 (88.54)	113 (87.60)			70 (87.50)	70 (87.50)

AC: Adjuvant chemotherapy; HIPEC: Hyperthermic intraperitoneal chemotherapy; PSM: Propensity score matching.

Citation: Lian WL, Cai LS, Lian MQ, Lian MJ, Sun YQ, Lv CB, Huang GP, Huang RJ, Zhang YB, Zeng WM, Xu QH, Zhu QJ, Chen QX. Efficacy and safety of sequential hyperthermic intraperitoneal chemotherapy following surgery for pathological T staging 4 gastric cancer. World J Gastroenterol 2026; 32(6): 115556
URL: https://www.wjgnet.com/1007-9327/full/v32/i6/115556.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i6.115556

Lian WL, Cai LS, Lian MQ, Lian MJ, Sun YQ, Lv CB, Huang GP, Huang RJ, Zhang YB, Zeng WM, Xu QH, Zhu QJ, Chen QX. Efficacy and safety of sequential hyperthermic intraperitoneal chemotherapy following surgery for pathological T staging 4 gastric cancer. World J Gastroenterol 2026; 32(6): 115556 [PMID: 41695288 DOI: 10.3748/wjg.v32.i6.115556]

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