Psychological and hematological factors associated with fatigue in patients with Crohn’s disease receiving pharmacological treatment

doi:10.3748/wjg.v32.i5.115673

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 7, 2026; 32(5): 115673
Published online Feb 7, 2026. doi: 10.3748/wjg.v32.i5.115673

Table 4 Association of fatigue with compound psychological/mental symptoms (depression, anxiety, stress and insomnia) in patients with Crohn’s disease treated at a referral center

Number of symptoms	Estimated logit (βx)	OR (vs score 0)
0	0.000	1.00
1	0.954	2.60
2	1.908	6.74
3	2.861	17.49
4	3.815	45.39

The chance of fatigue increases exponentially with the number of symptoms. Odds ratio by number of psychological symptoms (n = 100). OR: Odds ratio.

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Citation: Morais TC, Couto G, Silva BCD, Lisbôa RA, da Cruz BS, Viana MGF, de Sousa GBC, Arenas LP, Nery ES, Fortes FML, de Almeida NP, Pimentel AM, Fontes JAM, Surlo VC, Chebli JF, Rocha R, Santana GO. Psychological and hematological factors associated with fatigue in patients with Crohn’s disease receiving pharmacological treatment. World J Gastroenterol 2026; 32(5): 115673
URL: https://www.wjgnet.com/1007-9327/full/v32/i5/115673.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i5.115673

Morais TC, Couto G, Silva BCD, Lisbôa RA, da Cruz BS, Viana MGF, de Sousa GBC, Arenas LP, Nery ES, Fortes FML, de Almeida NP, Pimentel AM, Fontes JAM, Surlo VC, Chebli JF, Rocha R, Santana GO. Psychological and hematological factors associated with fatigue in patients with Crohn’s disease receiving pharmacological treatment. World J Gastroenterol 2026; 32(5): 115673 [PMID: 41693975 DOI: 10.3748/wjg.v32.i5.115673]

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