Identification of strong correlations of clearance with clinical outcomes for inflammatory bowel disease

Figure 1 Probability outcomes predicted by initial clearance. A: Mucosal healing; B: C-reactive protein normalization at 54 weeks; C: Composite endpoint; D: Development of antidrug antibody. Solid line is the median probability. Sharded areas represent the 95% confidence intervals (CIs), open symbols are individual clearance values. ADAFL: Positive for antidrug antibodies; CL: Clearance; Composite: A composite endpoint for mucosal healing, C-reactive protein normalization (less than 10 mg/L), Crohn’s Disease Activity Index, and fecal calprotectin at week 54; CRPFL2: C-reactive protein normalization (less than 10 mg/L) at week 54; MHEAL: Mucosal healing.