Danggui-Baishao herb pair protects against dextran sulfate sodium-induced colitis by modulating the Wnt/β-catenin pathway

Figure 9 Benzoylpaeoniflorin protected against dextran sulfate sodium-induced injury through activating β-catenin in vitro. A: Molecular docking of benzoylpaeoniflorin and β-catenin protein and their binding sites; B and C: Western blotting analysis of protein expression of Claudin1; D-F: Western blotting analysis of protein expression of β-catenin and Cyclin D1; G-I: Western blotting analysis of protein expression of Claudin1 and leucine-rich repeat-containing G-protein coupled receptor 5. For all the experiments: n = 4. ^aP < 0.05 vs dextran sulfate sodium group, ^cP < 0.001 vs dextran sulfate sodium group. ns: No significance compared with dextran sulfate sodium + ICG-001 group; DSS: Dextran sulfate sodium; Lgr5: Leucine-rich repeat-containing G-protein coupled receptor 5; Ben: Benzoylpaeoniflorin.