Danggui-Baishao herb pair protects against dextran sulfate sodium-induced colitis by modulating the Wnt/β-catenin pathway

Figure 2 Herb pair inhibited intestinal inflammation in colitis mice. A: Quantitative polymerase chain reaction (qPCR) analysis of mRNA expression of tumor necrosis factor, interleukin 6, interleukin 1b, interleukin 18, interferon-gamma, interleukin 13, and interleukin 10 in colon tissues; B: QPCR analysis of mRNA expression of toll-like receptor 4 in colon tissues; C: QPCR analysis of mRNA expression of V-rel reticuloendotheliosis viral oncogene homolog A in colon tissues; D: Representative images of immunohistochemical (IHC) of CD11b and F4/80 in colon tissues; E and F: Quantitative analysis of IHC results of CD11b and F4/80. For qPCR analysis: n = 5-6, for IHC measurement: n = 3. ^aP < 0.05 vs dextran sulfate sodium group, ^bP < 0.01 vs dextran sulfate sodium group, ^cP < 0.001 vs dextran sulfate sodium group. Tnf: Tumor necrosis factor; Il6: Interleukin 6; Il1b: Interleukin 1b; Il18: Interleukin 18; Ifng: Interferon-gamma; Il13: Interleukin 13; Il10: Interleukin 10; DSS: Dextran sulfate sodium.