Integrating proteomics, metabolomics, and molecular docking to elucidate the mechanism of Jiangtang Qingre formula against metabolic dysfunction-associated steatohepatitis

doi:10.3748/wjg.123033

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Dec 28, 2026; 32(48): 123033
Published online Dec 28, 2026. doi: 10.3748/wjg.123033

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Figure 3 Jiangtang Qingre formula mitigates hepatic oxidative stress in methionine-choline-deficient diet-induced metabolic dysfunction-associated steatohepatitis mice (n = 8). A: Serum and hepatic free fatty acids; B: Hepatic malondialdehyde; C: Hepatic total superoxide dismutase; D; Hepatic glutathione peroxidase. ^aP < 0.001 vs methionine-choline-sufficient group; ^bP < 0.05 vs methionine-choline-deficient (MCD) group; ^cP < 0.01 vs MCD group; ^dP < 0.001 vs MCD group. MCD: Methionine-choline-deficient; MCS: Methionine-choline-sufficient; PPC: Phosphatidylcholine capsules; JQF: Jiangtang Qingre formula; JQFH: Jiangtang Qingre formula-high; FFA: Free fatty acids; MDA: Malondialdehyde; T-SOD: Total superoxide dismutase; GSH-Px: Glutathione peroxidase.

Citation: Zhou LJ, Wu JL, Wang H, Han R, Tang C, Fang F, Zhu DP. Integrating proteomics, metabolomics, and molecular docking to elucidate the mechanism of Jiangtang Qingre formula against metabolic dysfunction-associated steatohepatitis. World J Gastroenterol 2026; 32(48): 123033
URL: https://www.wjgnet.com/1007-9327/full/v32/i48/123033.htm
DOI: https://dx.doi.org/10.3748/wjg.123033

Zhou LJ, Wu JL, Wang H, Han R, Tang C, Fang F, Zhu DP. Integrating proteomics, metabolomics, and molecular docking to elucidate the mechanism of Jiangtang Qingre formula against metabolic dysfunction-associated steatohepatitis. World J Gastroenterol 2026; 32(48): 123033 [DOI: 10.3748/wjg.123033]

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