Zfp36 zinc finger CCCH-type inhibits gastric cancer progression by upregulating lipase G and binding its 3’ untranslated region

Figure 1 ZFP36 inhibits cell proliferation, migration, invasion, and facilitates apoptosis in AGS cells. A: Validation of ZFP36 overexpression efficiency by reverse transcription-quantitative polymerase chain reaction in AGS cells; B: Validation of ZFP36 overexpression efficiency by western blot in AGS cells; C: Cell proliferation assessed by cell counting kit-8 assay; D: Cell cycle distribution analyzed by flow cytometry; E: Cell apoptosis detected by flow cytometry; F: Cell invasion assessed by Transwell assay; G: Cell migration assessed by Transwell assay. ^aP < 0.05 vs negative control group, ^bP < 0.01 vs negative control group, ^cP < 0.001 vs negative control group, ^dP < 0.0001 vs negative control group. NC: Negative control; OE: Overexpression.