Radiomics and deep learning predict neoadjuvant immunochemotherapy response in locally advanced esophageal squamous cell carcinoma

doi:10.3748/wjg.124166

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Dec 14, 2026; 32(46): 124166
Published online Dec 14, 2026. doi: 10.3748/wjg.124166

Table 4 Brier score of the best performing models developing on different kind of features

	Train	Internal validation	External validation
Clinical model	0.026	0.131	0.279
Radiomics model	0.030	0.164	0.323
Deep learning model	0.058	0.179	0.294
Radiomics-deep learning models	0.052	0.182	0.189
Clinical-radiomics-deep learning models	< 0.001	0.168	0.296

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Citation: Zhao BX, Zhang M, Fu WQ, Li XY, Han ML, Zhang J, Gao W, Guo TH, Li HY, Ai SW, Wang HJ, Zhang BY, Wang Q. Radiomics and deep learning predict neoadjuvant immunochemotherapy response in locally advanced esophageal squamous cell carcinoma. World J Gastroenterol 2026; 32(46): 124166
URL: https://www.wjgnet.com/1007-9327/full/v32/i46/124166.htm
DOI: https://dx.doi.org/10.3748/wjg.124166

Zhao BX, Zhang M, Fu WQ, Li XY, Han ML, Zhang J, Gao W, Guo TH, Li HY, Ai SW, Wang HJ, Zhang BY, Wang Q. Radiomics and deep learning predict neoadjuvant immunochemotherapy response in locally advanced esophageal squamous cell carcinoma. World J Gastroenterol 2026; 32(46): 124166 [DOI: 10.3748/wjg.124166]

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