Clinical features and biomarkers associated with ulcerative colitis: A systematic review and meta-analysis

doi:10.3748/wjg.123374

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Meta-Analysis

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Dec 14, 2026; 32(46): 123374
Published online Dec 14, 2026. doi: 10.3748/wjg.123374

Table 1 Baseline characteristics and geographical distribution of the included studies

Diseases	Continent
Diseases	North America	Asia	Oceania	Africa	South America	Europe	Total
UC	6457	71488	19	6	161	40218	118349
ITB	0	394	0	0	0	0	394
IBS	0	319	0	0	0	0	319
IE	0	247	0	0	0	0	247
HCs	40147	7664	0	0	60	69892	117763
CD	8772	28984	41	9	111	22724	60641
IC	0	602	0	0	0	0	602
IBD-U	38	208	0	0	5	338	589
Other	156	2347	0	0	0	13	2516
Total	55570	112253	60	15	337	133185	301420

UC: Ulcerative colitis; ITB: Intestinal tuberculosis; IBS: Irritable bowel syndrome; IE: Infectious enteritis; HCs: Healthy controls; CD: Crohn’s disease; IC: Ischemic colitis; IBD-U: Inflammatory bowel disease unclassified; Other: Unspecified diseases.

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Citation: Liu K, Zhang XH, Zhou XY, Liu YX, Pan SQ, Liu TX, Russell R, Wang XH, Yao YP, Zhao XJ, Sun HY, Ju CL, Liu JP, Liu ZL. Clinical features and biomarkers associated with ulcerative colitis: A systematic review and meta-analysis. World J Gastroenterol 2026; 32(46): 123374
URL: https://www.wjgnet.com/1007-9327/full/v32/i46/123374.htm
DOI: https://dx.doi.org/10.3748/wjg.123374

Liu K, Zhang XH, Zhou XY, Liu YX, Pan SQ, Liu TX, Russell R, Wang XH, Yao YP, Zhao XJ, Sun HY, Ju CL, Liu JP, Liu ZL. Clinical features and biomarkers associated with ulcerative colitis: A systematic review and meta-analysis. World J Gastroenterol 2026; 32(46): 123374 [DOI: 10.3748/wjg.123374]

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