Gluten-free diet reduces severity of dextran sulfate sodium-induced colitis in BALB/c mice

Figure 7 Changes of γδ T cells in mesenteric lymph nodes and spleen of dextran sulfate sodium-treated mice fed gluten-free diet and standard diet. A: Increased proportion of cluster of differentiation (CD) 3⁺ γδ⁺ T cells in mesenteric lymph nodes (MLN) and spleen of female BALB/c mice fed gluten-free diet vs standard diet (n = 8, P < 0.05) after 7 days of 2.5% dextran sulfate sodium; B: Example dot plots of γδ T cells in spleen; C: There were no changes in the proportion of CD8^- vs CD8⁺ γδ T-cell subsets; D: CD8^-/CD8⁺ γδ⁺ T cells in MLN. Data are expressed as mean ± SD. ^aP < 0.05. The results represent an example from two independent experiments. MLN: Mesenteric lymph nodes; STD: Standard diet; GFD: Gluten-free diet; CD: Cluster of differentiation; TCR: T cell receptor; SSC-A: Side scatter-area; PE-Cy7: Phycoerythrin-cyanine 7.