Impact of glucagon-like peptide-1 receptor agonists on bowel preparation quality for colonoscopy in type 2 diabetes

doi:10.3748/wjg.121313

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World Journal of Gastroenterology

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1007-9327

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Retrospective Cohort Study

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World J Gastroenterol. Dec 14, 2026; 32(46): 121313
Published online Dec 14, 2026. doi: 10.3748/wjg.121313

Table 2 Procedural outcomes of glucagon-like peptide-1 receptor agonist users and dipeptidyl peptidase-4 inhibitor users before and after matching, mean ± SD/n (%)

	Before matching (n = 589)				After matching (n = 341)
	Total (n = 589)	GLP-1RA (n = 153)	DPP-4i (n = 346)	P value	Total (n = 341)	GLP-1RA (n = 133)	DPP-4i (n = 208)	P value
Total BBPS	6.9 ± 1.7	6.6 ± 2.0	7.0 ± 1.7	0.058	6.8 ± 1.8	6.6 ± 2.0	7.0 ± 1.6	0.116
Segment BBPS
Left	2.4 ± 0.7	2.3 ± 0.8	2.4 ± 0.7	0.051	2.3 ± 0.8	2.2 ± 0.8	2.4 ± 0.7	0.275
Transverse	2.5 ± 0.6	2.4 ± 0.7	2.5 ± 0.6	0.342	2.5 ± 0.6	2.4 ± 0.7	2.5 ± 0.6	0.413
Right	2.0 ± 0.7	1.9 ± 0.8	2.1 ± 0.7	0.026	2.0 ± 0.7	1.9 ± 0.8	2.1 ± 0.7	0.031
Inadequate bowel preparation¹	102 (17.3)	36 (23.5)	66 (15.1)	0.025	66 (19.4)	34 (25.6)	32 (15.4)	0.034
Aborted colonoscopy	5 (0.8)	2 (1.3)	3 (0.7)	0.609	3 (0.9)	2 (1.5)	1 (0.5)	0.569
Repeat colonoscopy	5 (0.8)	2 (1.3)	3 (0.7)	0.609	3 (0.9)	2 (1.5)	1 (0.5)	0.569

¹Inadequate bowel preparation was defined as total Boston Bowel Preparation Scale score < 6 or any segment of Boston Bowel Preparation Scale score < 2.

BBPS: Boston Bowel Preparation Scale; DPP-4i: Dipeptidyl peptidase-4 inhibitor; GLP-1RA: Glucagon-like peptide-1 receptor agonist.

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Citation: Park HJ, Oh YE, Chi SA, Kim M, Kim JE, Hong SN, Min BH, Kim YH, Chang DK, Kim TS, Kim ER. Impact of glucagon-like peptide-1 receptor agonists on bowel preparation quality for colonoscopy in type 2 diabetes. World J Gastroenterol 2026; 32(46): 121313
URL: https://www.wjgnet.com/1007-9327/full/v32/i46/121313.htm
DOI: https://dx.doi.org/10.3748/wjg.121313

Park HJ, Oh YE, Chi SA, Kim M, Kim JE, Hong SN, Min BH, Kim YH, Chang DK, Kim TS, Kim ER. Impact of glucagon-like peptide-1 receptor agonists on bowel preparation quality for colonoscopy in type 2 diabetes. World J Gastroenterol 2026; 32(46): 121313 [DOI: 10.3748/wjg.121313]

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