Narrow-band imaging-modified Kyoto score predicts pathological upgrading after endoscopic submucosal dissection in gastric intraepithelial neoplasia

Table 3 Univariable and multivariable logistic regression analysis for pathological upgrading

Variable	Univariable analysis		Multivariable analysis
	OR (95%CI)	P value	OR (95%CI)	P value
Lesion size ≥ 20 mm	2.110 (1.223-3.642)	0.007	2.314 (0.930-5.762)	0.071
Type IIc morphology	3.164 (1.578-6.341)	0.001	1.017 (0.289-3.583)	0.979
Surface redness	2.616 (1.511-4.528)	< 0.001	0.564 (0.196-1.628)	0.290
Helicobacter pylori status	1.864 (1.087-3.197)	0.024	0.978 (0.433-2.208)	0.958
NBI-modified Kyoto score	9.111 (5.257-15.790)	< 0.001	14.781 (6.621-32.997)1	< 0.001
Conventional Kyoto score	7.438 (4.194-13.191)	< 0.001	N/A2	N/A

¹The narrow-band imaging-modified Kyoto score was analyzed as a categorical variable (≥ 4 vs < 4) in the logistic regression model.

²The conventional Kyoto score was not included in the multivariable model because of overlapping components and conceptual redundancy with the narrow-band imaging-modified Kyoto score.

The reference categories were lesion size < 20 mm, non-IIc morphology, absence of surface redness, past/never Helicobacter pylori infection, and narrow-band imaging-modified Kyoto score < 4, as applicable. OR: Odds ratio; CI: Confidence interval; NBI: Narrow-band imaging; N/A: Not applicable.