Multi-omics analysis identifies COX6A2/SCF/c-Kit-mediated mitochondrial remodeling as a key mechanism of Tangwei’an decoction in diabetic gastroparesis

Figure 6 Tangwei’an regulates mitochondrial dynamics in diabetic gastroparesis mice via modulation of COX6A2. A-D: Representative western blots and densitometric quantification of COX6A2, SCF and c-Kit in gastric tissues (n = 3); E-G: Representative western blots and densitometric quantification of DRP1 and MFN2 in gastric tissues (n = 3); H: ATP content in mice gastric tissues (n = 6). Data are presented as the mean ± SEM. ^bP < 0.01 vs Control group, ^dP < 0.01 vs the Model group. TWA: Tangwei’an.