Multi-omics analysis identifies COX6A2/SCF/c-Kit-mediated mitochondrial remodeling as a key mechanism of Tangwei’an decoction in diabetic gastroparesis

Figure 5 Integrated analysis of proteomics and metabolomics. A: Venn diagram illustrating the overlapping Kyoto Encyclopedia of Genes and Genomes pathways enriched by differentially expressed proteins (DEPs) and differentially expressed metabolites (DEMs); B: Integrated proteomic and metabolomic Kyoto Encyclopedia of Genes and Genomes bubble plot; C: Analyzing the correlation between DEPs and DEMs; D: Correlation network map of DEPs and DEMs; E: Molecular docking of COX6A2 with Nobiletin; F: Molecular docking of COX6A2 with atractylenolide II. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001.