Dendrobium officinale polysaccharides attenuates spasmolytic polypeptide-expressing metaplasia via dual modulation of gastric epithelial cell fate and macrophage polarization

Figure 1 The Dendrobium officinale polysaccharides effects on mouse body weight, pathological improvement, mucus types and levels of interleukin-13 and interleukin-33 on spasmolytic polypeptide-expressing metaplasia model. A: Mouse body weight; B: Pathological improvement; C: Mucus types; D and E: Levels of interleukin-13 and interleukin-33. The data are represented as mean ± SD, n = 6. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001, vs control; ^dP < 0.05, ^eP < 0.01, ^fP < 0.001, vs spasmolytic polypeptide-expressing metaplasia model. Ctrl: Control; SPEM: Spasmolytic polypeptide-expressing metaplasia; WFC: Weifuchun capsule; H-DOP: High-dose Dendrobium officinale polysaccharides; L-DOP: Low-dose Dendrobium officinale polysaccharides; IL: Interleukin.