Association of smaller-diameter underdilation of transjugular intrahepatic portosystemic shunt stents with improved long-term survival: A propensity score-matched study

doi:10.3748/wjg.121243

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World Journal of Gastroenterology

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1007-9327

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Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Dec 7, 2026; 32(45): 121243
Published online Dec 7, 2026. doi: 10.3748/wjg.121243

Table 3 Prognostic factors identified via Cox regression after propensity score matching

Characteristics	Univariate		Multivariate
Characteristics	Hazard ratio (95%CI)	P value	Hazard ratio (95%CI)	P value
Age	1.031 (0.997-1.065)	0.075
Sex
Male	Reference
Female	0.534 (0.253-1.127)	0.100
BMI	0.999 (0.905-1.103)	0.982
Etiology of cirrhosis		0.584
Hepatitis B cirrhosis	Reference
Hepatitis C cirrhosis	0.606 (0.181-2.031)	0.417
Alcoholic cirrhosis	1.031 (0.416-2.555)	0.948
Autoimmune hepatitis	0.351 (0.082-1.499)	0.158
Others	0.714 (0.288-1.772)	0.468
Indication for TIPS
Variceal bleeding	Reference
Refractory ascites/hydrothorax	3.987 (1.552-10.244)	0.004
Child sore	1.363 (1.102-1.686)	0.004
Child-Pugh grade		0.001		0.039
A	Reference		Reference
B	1.795 (0.862-3.902)	0.140	0.864 (0.256-2.911)	0.813
C	6.203 (2.299-16.738)	0.000	2.759 (0.685-11.107)	0.153
MELD 3.0 score	1.118 (1.020-1.225)	0.017
Liver cancer
No	Reference		Reference
Yes	3.558 (1.558-8.124)	0.003	2.755 (1.129-6.721)	0.026
Diabetes
No	Reference
Yes	1.438 (0.713-2.901)	0.310
Hypertension
No	Reference
Yes	1.386 (0.579-3.319)	0.464
Ascites
No	Reference		Reference
Yes	2.556 (1.171-5.577)	0.018	3.894 (1.022-14.841)	0.046
Ascites grade		0.001
No	Reference
Mild	1.633 (0.630-4.234)	0.313
Moderate	1.838 (0.638-5.298)	0.260
Large	5.074 (2.150-11.979)	0.000
Hydrothorax
No	Reference
Yes	1.770 (0.928-3.375)	0.083
PVT
No	Reference
Yes	1.644 (0.850-3.179)	0.140
Post-TIPS PPG	0.988 (0.924-1.056)	0.716
Balloon diameter
≥ 7 mm	Reference		Reference
≤ 6 mm	0.430 (0.212-0.869)	0.019	0.422 (0.203-0.877)	0.021
Albumin	0.959 (0.906-1.015)	0.147
TBIL	1.019 (0.997-1.042)	0.095
Creatinine	1.001 (0.992-1.010)	0.854
PT	1.108 (0.927-1.324)	0.261
INR	4.130 (0.760-22.438)	0.100
White blood cell	1.001 (0.828-1.212)	0.988
Platelet	0.999 (0.993-1.005)	0.747

CI: Confidence interval; BMI: Body mass index; TIPS: Transjugular intrahepatic portosystemic shunt; MELD: Model for end-stage liver disease; PVT: Portal vein thrombosis; PPG: Portal pressure gradient; TBIL: Total bilirubin; PT: Prothrombin time; INR: International normalized ratio.

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Citation: Zhang WQ, Li KJ, Yang F, Jiang GJ, Zhang L, Jiang H, Guo H, Li SW. Association of smaller-diameter underdilation of transjugular intrahepatic portosystemic shunt stents with improved long-term survival: A propensity score-matched study. World J Gastroenterol 2026; 32(45): 121243
URL: https://www.wjgnet.com/1007-9327/full/v32/i45/121243.htm
DOI: https://dx.doi.org/10.3748/wjg.121243

Zhang WQ, Li KJ, Yang F, Jiang GJ, Zhang L, Jiang H, Guo H, Li SW. Association of smaller-diameter underdilation of transjugular intrahepatic portosystemic shunt stents with improved long-term survival: A propensity score-matched study. World J Gastroenterol 2026; 32(45): 121243 [DOI: 10.3748/wjg.121243]

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