Microbiota-nutrition sequential therapy for refractory radiation proctitis: A case report

Figure 4 Predicted Kyoto Encyclopedia of Genes and Genomes level 2 functional profiles of the patient before and after fecal microbiota transplantation. A: Relative abundances of Kyoto Encyclopedia of Genes and Genomes level 2 pathways across pre-fecal microbiota transplantation (FMT), FMT-1, FMT-2, and two donor samples (Donor1, Donor2), grouped by level 1 categories (Metabolism, Genetic Information Processing, Environmental Information Processing, Cellular Processes, Organismal Systems, Human Diseases, Brite Hierarchies, and Unclassified); B: Detailed abundance patterns of individual level 2 pathways, highlighting functional modules with notable shifts after FMT. Predictions were generated using PICRUSt2 from 16S rRNA sequencing data. pre-FMT: Baseline before fecal microbiota transplantation; FMT-1: 1 month after the first fecal microbiota transplantation; FMT-2: 2 months after the second fecal microbiota transplantation; Donor1/Donor2: Fecal microbiota donors.