Mitochondrial dysfunction in patients with celiac disease: A multidimensional study

doi:10.3748/wjg.122239

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Nov 28, 2026; 32(44): 122239
Published online Nov 28, 2026. doi: 10.3748/wjg.122239

Table 1 Demographic and disease characteristics of celiac disease patients and healthy controls, mean ± SD/median (interquartile range)/n (%)

Characteristic	Parameter	CeD group (n = 18)	Control group (n = 18)	P value
Demographic characteristics	Age (years)	51.33 ± 8.89	50.11 ± 8.20	0.1124¹
	Female	11 (61.1)	11 (61.1)	1²
	BMI (kg/m²)	21.59 ± 3.86	22.41 ± 2.843	0.4365¹
	Smoking history	6 (33.3)	7 (38.9)	1²
	Alcohol consumption history	0	1 (5.6)	1²
Disease characteristics	Symptom duration (months)	15 (1.75-48.5)	-	-
	Modified Marsh grade
	IIIa	15 (83.3)	0	-
	IIIb	3 (16.7)	0	-
	IIIc	0	0	-
	Serum anti-tTG-IgA titer (CU)	479.3 (292.4-3021)	1.9 (lower detection limit)	-

¹P values were calculated using the paired t-test (for age and body mass index).

²P values were calculated using the McNemar’s exact test (for sex).

CeD: Celiac disease; BMI: Body mass index; tTG: Tissue transglutaminase; IgA: Immunoglobulin A.

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Citation: Habudai B, Xue SL, Kong WJ, Yu L, Shi T, Xie JJ, Maimaiti R, Gao F. Mitochondrial dysfunction in patients with celiac disease: A multidimensional study. World J Gastroenterol 2026; 32(44): 122239
URL: https://www.wjgnet.com/1007-9327/full/v32/i44/122239.htm
DOI: https://dx.doi.org/10.3748/wjg.122239

Habudai B, Xue SL, Kong WJ, Yu L, Shi T, Xie JJ, Maimaiti R, Gao F. Mitochondrial dysfunction in patients with celiac disease: A multidimensional study. World J Gastroenterol 2026; 32(44): 122239 [DOI: 10.3748/wjg.122239]

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