Emodin ameliorates cholestatic liver injury by regulating bile acid metabolism and gut microbiota in mice

Figure 9 Spearman’s correlation analyses between the relative abundance of gut microbiota at the genus level and bile acids. A: The correlations between gut microbiota and bile acids between the control and α-naphthylisothiocyanate (ANIT) group; B: The correlations between gut microbiota and bile acids between the ANIT and emodin-ANIT group. Data were analyzed via two-tailed test of significance. ^aP < 0.05 vs control group, ^bP < 0.01 vs control group, ^cP < 0.001 vs control group, ^dP < 0.05 vs α-naphthylisothiocyanate group, ^eP < 0.01 vs α-naphthylisothiocyanate group, and ^fP < 0.001 vs α-naphthylisothiocyanate group.