Real-world effectiveness and safety of risankizumab in multirefractory Crohn’s disease: A multicenter AIRIS-Crohn registry analysis

doi:10.3748/wjg.119693

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World Journal of Gastroenterology

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1007-9327

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Nov 14, 2026; 32(42): 119693
Published online Nov 14, 2026. doi: 10.3748/wjg.119693

Table 3 Clinical remission by line of therapy, n (%)

Line of therapy¹	Baseline	6 months	12 months	P value
First line (n = 30)	7 (24.1)	9 (81.8)	5 (83.3)	0.021 at 6 months
Second line (n = 72)	19 (26.4)	23 (54.8)	9 (56.3)
Third line (n = 96)	15 (15.6)	26 (39.4)	9 (42.9)

¹Clinical remission rates at baseline, 6 and 12 months, stratified by line of therapy.

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Citation: Caballero-Mateos AM, Valdés-Delgado T, Olmedo-Martín R, Romero-Cara P, Martín-Rodríguez MDM, Lancho Muñoz A, Moreno-Barrueco M, Gijón-Villanova R, Fernández-Moreno N, Rodríguez-González FJ, Hernández-Martínez Á, Trapero-Martínez AM, Bejarano-García A, Benitez Cantero JM, Mata-Perdigón FJ, Sáez-Díaz A, Argüelles-Arias F. Real-world effectiveness and safety of risankizumab in multirefractory Crohn’s disease: A multicenter AIRIS-Crohn registry analysis. World J Gastroenterol 2026; 32(42): 119693
URL: https://www.wjgnet.com/1007-9327/full/v32/i42/119693.htm
DOI: https://dx.doi.org/10.3748/wjg.119693

Caballero-Mateos AM, Valdés-Delgado T, Olmedo-Martín R, Romero-Cara P, Martín-Rodríguez MDM, Lancho Muñoz A, Moreno-Barrueco M, Gijón-Villanova R, Fernández-Moreno N, Rodríguez-González FJ, Hernández-Martínez Á, Trapero-Martínez AM, Bejarano-García A, Benitez Cantero JM, Mata-Perdigón FJ, Sáez-Díaz A, Argüelles-Arias F. Real-world effectiveness and safety of risankizumab in multirefractory Crohn’s disease: A multicenter AIRIS-Crohn registry analysis. World J Gastroenterol 2026; 32(42): 119693 [DOI: 10.3748/wjg.119693]

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