Epitranscriptomic regulation of the COX-2/PGE2 axis by hnRNPA2B1 promotes esophageal squamous cell carcinoma progression

doi:10.3748/wjg.121890

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Nov 7, 2026; 32(41): 121890
Published online Nov 7, 2026. doi: 10.3748/wjg.121890

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Figure 7 Schematic model illustrating the hnRNPA2B1-cyclooxygenase-2/prostaglandin E2 axis in esophageal squamous cell carcinoma progression. (Created in BioRender. https://BioRender.com/5wlddw2). LGIN: Low-grade intraepithelial neoplasia; HGIN: High-grade intraepithelial neoplasia; ESCC: Esophageal squamous cell carcinoma; PGE2: Prostaglandin E2; COX-2: Cyclooxygenase-2; m6A: N6-methyladenosine.

Citation: Lu JQ, Fang XF, Guo XX, Liu M, Lin JH, Zheng HL, Zhong CM, Lin QY, Huang XY, Wang XZ, Tian H, Que JW, Chen FL, Zheng BY. Epitranscriptomic regulation of the COX-2/PGE2 axis by hnRNPA2B1 promotes esophageal squamous cell carcinoma progression. World J Gastroenterol 2026; 32(41): 121890
URL: https://www.wjgnet.com/1007-9327/full/v32/i41/121890.htm
DOI: https://dx.doi.org/10.3748/wjg.121890

Lu JQ, Fang XF, Guo XX, Liu M, Lin JH, Zheng HL, Zhong CM, Lin QY, Huang XY, Wang XZ, Tian H, Que JW, Chen FL, Zheng BY. Epitranscriptomic regulation of the COX-2/PGE2 axis by hnRNPA2B1 promotes esophageal squamous cell carcinoma progression. World J Gastroenterol 2026; 32(41): 121890 [DOI: 10.3748/wjg.121890]

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