Baseline cytokines and programmed death-ligand 1 prognostic value in advanced gastric cancer with sintilimab plus chemotherapy

doi:10.3748/wjg.120447

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Oct 28, 2026; 32(40): 120447
Published online Oct 28, 2026. doi: 10.3748/wjg.120447

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Figure 5 Least absolute shrinkage and selection operator-Cox regularization for overall survival. A: Ten-fold cross-validation curve of partial likelihood deviance vs log(λ); vertical lines indicate λ.min and λ.1se; B: Coefficient shrinkage paths for all candidate variables. At λ.1se, interleukin (IL)-10 high and IL-17 high were retained as core predictors; IL-6, programmed death-ligand 1, and Epstein-Barr virus were additionally selected at λ.min (n = 101). OS: Overall survival; CV: Cross validation; EBV: Epstein-Barr virus; IL: Interleukin; PD-L1: Programmed death-ligand 1.

Citation: Li YC, Pan D, Liu HN, Pei ZC, Li YQ, Han ZX, Liu WL. Baseline cytokines and programmed death-ligand 1 prognostic value in advanced gastric cancer with sintilimab plus chemotherapy. World J Gastroenterol 2026; 32(40): 120447
URL: https://www.wjgnet.com/1007-9327/full/v32/i40/120447.htm
DOI: https://dx.doi.org/10.3748/wjg.120447

Li YC, Pan D, Liu HN, Pei ZC, Li YQ, Han ZX, Liu WL. Baseline cytokines and programmed death-ligand 1 prognostic value in advanced gastric cancer with sintilimab plus chemotherapy. World J Gastroenterol 2026; 32(40): 120447 [DOI: 10.3748/wjg.120447]

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