Baseline cytokines and programmed death-ligand 1 prognostic value in advanced gastric cancer with sintilimab plus chemotherapy

Figure 4 Least absolute shrinkage and selection operator-Cox regularization for progression-free survival. A: Ten-fold cross-validation curve showing partial likelihood deviance as a function of log(λ); vertical dashed line indicates λ.min and dot-dashed line indicates λ.1se. Numbers along the top axis represent the count of non-zero coefficients at each λ; B: Coefficient shrinkage paths for all candidate variables; vertical lines correspond to λ.min and λ.1se. Three variables [interleukin (IL)-6 high, IL-10 high, IL-17 high] were retained at λ.1se. (n = 101). PFS: Progression-free survival; CV: Cross validation; EBV: Epstein-Barr virus; IL: Interleukin; PD-L1: Programmed death-ligand 1.