Baseline cytokines and programmed death-ligand 1 prognostic value in advanced gastric cancer with sintilimab plus chemotherapy

doi:10.3748/wjg.120447

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Oct 28, 2026; 32(40): 120447
Published online Oct 28, 2026. doi: 10.3748/wjg.120447

Table 6 Multivariable firth-penalized Cox regression for overall survival

Variable	HR (95%CI)	P value
IL-10: High vs low	3.35 (1.45-7.81)	0.005
IL-17: High vs low	3.94 (1.93-8.11)	< 0.001
Chemo regimen: Taxane vs platinum-doublet	0.87 (0.5-1.5)	0.623
PD-L1: Positive vs negative	0.32 (0.14-0.77)	0.012
EBV: Positive vs negative	2.9 (1.09-6.73)	0.034

IL: Interleukin; PD-L1: Programmed death-ligand 1; EBV: Epstein-Barr virus.

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Citation: Li YC, Pan D, Liu HN, Pei ZC, Li YQ, Han ZX, Liu WL. Baseline cytokines and programmed death-ligand 1 prognostic value in advanced gastric cancer with sintilimab plus chemotherapy. World J Gastroenterol 2026; 32(40): 120447
URL: https://www.wjgnet.com/1007-9327/full/v32/i40/120447.htm
DOI: https://dx.doi.org/10.3748/wjg.120447

Li YC, Pan D, Liu HN, Pei ZC, Li YQ, Han ZX, Liu WL. Baseline cytokines and programmed death-ligand 1 prognostic value in advanced gastric cancer with sintilimab plus chemotherapy. World J Gastroenterol 2026; 32(40): 120447 [DOI: 10.3748/wjg.120447]

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