Urinary trypsinogens and trypsinogen activation peptide as biomarkers in pediatric acute pancreatitis: A prospective observational study

doi:10.3748/wjg.119619

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Observational Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Oct 28, 2026; 32(40): 119619
Published online Oct 28, 2026. doi: 10.3748/wjg.119619

Table 3 Urinary biomarkers at three time points in acute pancreatitis, mean ± SD

Parameter	Within 24 hours	After 48 hours	After 72 hours	P value
Trypsinogen-1 (ng/mL)	0.91 ± 0.80	0.86 ± 0.59	0.79 ± 0.49	0.164
Trypsinogen-2 (ng/mL)	0.50 ± 0.86	0.64 ± 1.19	0.38 ± 0.19	0.670
TAP (pg/mL)	52.91 ± 48.60	42.21 ± 39.74	42.79 ± 28.32	0.504

P < 0.05 is statistically significant. TAP: Trypsinogen activation peptide.

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Citation: Kwiatek-Średzińska KA, Trochimczyk K, Jamiołkowski J, Lebensztejn DM. Urinary trypsinogens and trypsinogen activation peptide as biomarkers in pediatric acute pancreatitis: A prospective observational study. World J Gastroenterol 2026; 32(40): 119619
URL: https://www.wjgnet.com/1007-9327/full/v32/i40/119619.htm
DOI: https://dx.doi.org/10.3748/wjg.119619

Kwiatek-Średzińska KA, Trochimczyk K, Jamiołkowski J, Lebensztejn DM. Urinary trypsinogens and trypsinogen activation peptide as biomarkers in pediatric acute pancreatitis: A prospective observational study. World J Gastroenterol 2026; 32(40): 119619 [DOI: 10.3748/wjg.119619]

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