Urinary trypsinogens and trypsinogen activation peptide as biomarkers in pediatric acute pancreatitis: A prospective observational study

Table 1 Urinary biomarkers in patients with acute pancreatitis and controls, mean ± SD

Parameter	Patients with AP (n = 61)	Control group (n = 29)	P value
Trypsinogen-1 within 24 hours (ng/mL)	0.91 ± 0.80	0.86 ± 0.43	0.137
Trypsinogen-1 after 48 hours (ng/mL)	0.86 ± 0.59	0.86 ± 0.43	0.384
Trypsinogen-1 after 72 hours (ng/mL)	0.79 ± 0.49	0.86 ± 0.43	0.111
Trypsinogen-2 within 24 hours (ng/mL)	0.50 ± 0.86	0.30 ± 0.12	0.117
Trypsinogen-2 after 48 hours (ng/mL)	0.64 ± 1.19	0.30 ± 0.12	0.022
Trypsinogen-2 after 72 hours (ng/mL)	0.38 ± 0.19	0.30 ± 0.12	0.144
TAP within 24 hours (pg/mL)	52.91 ± 48.60	44.70 ± 22.08	0.963
TAP after 48 hours (pg/mL)	42.21 ± 39.74	44.70 ± 22.08	0.143
TAP after 72 hours (pg/mL)	42.79 ± 28.32	44.70 ± 22.08	0.503

P < 0.05 is statistically significant. AP: Acute pancreatitis; TAP: Trypsinogen activation peptide.