ARPC1B contributes to colorectal cancer progression and is associated with programmed death-ligand 1 expression

Figure 3 Knockdown of ARPC1B inhibits tumor growth and metastasis in xenograft nude mice model. A: The image showed the HT29-xenograft nude mice model was successful established; B: The image showed the tumors obtained from nude mice model; C: The tumor weight of HT29-negative control (NC)-ARPC1B or HT29-ARPC1B-short hairpin RNA (shRNA) (sh-ARPC1B) xenograft nude mice models; D: The tumor volume of HT29-NC-ARPC1B or HT29-sh-ARPC1B xenograft nude mice models; E: The image showed the SW620-xenograft nude mice model was successful established; F: The image showed the tumors obtained from nude mice model; G: The tumor weight of SW620-NC-ARPC1B or SW620-sh-ARPC1B xenograft nude mice models; H: The tumor volume of SW620-NC-ARPC1B or SW620-sh-ARPC1B xenograft nude mice models (n = 5); I: The metastasis of colorectal cancer (CRC) induced by HT29 in nude mice was presented by bioluminescence and fluorescence imaging; J: The metastasis of CRC induced by SW620 in nude mice was presented by bioluminescence and fluorescence imaging (n = 3). ^cP < 0.001. NC: Negative control; sh-ARPC1B: ARPC1B-short hairpin RNA.