ARPC1B contributes to colorectal cancer progression and is associated with programmed death-ligand 1 expression

Figure 2 Knockdown of ARPC1B suppresses the malignant phenotype of colorectal cancer cell. A: The knockdown efficiency of ARPC1B-short hairpin RNA (shRNA) 1-3 in HT29 and SW620 cell lines; B: The proliferation of HT29 and SW620 cell lines treated or not treated with ARPC1B-shRNA (sh-ARPC1B) was detected via cell counting kit-8 assay; C: The invasion of HT29 and SW620 cell lines treated or not treated with sh-ARPC1B was detected via transwell assay; D: The apoptosis rate of HT29 and SW620 cell lines treated or not treated with sh-ARPC1B was detected via flow-cytometry assay. n = 3. scale bar = 100 μm. ^aP < 0.05. ^bP < 0.01. ^cP < 0.001. NC: Negative control; sh-ARPC1B: ARPC1B-short hairpin RNA; FITC: Fluorescein isothiocyanate; PI: Propidium iodide.