Synergistic anti-hepatoma effect of triptolide and quercetin via co-inhibition and interaction with Janus kinase and mammalian target of rapamycin signal pathway

Figure 11  The expression level of related mechanism protein. A: Western blots showing the levels of Janus kinase 1, p-signal transducer and activator of transcription 3, phosphoinositide 3-kinase, p-phosphoinositide 3-kinase, protein kinase B, p-protein kinase B, mammalian target of rapamycin, and p-mammalian target of rapamycin; B: The expression of each protein normalized by β-actin according to grey value. ^aP < 0.05. TP: Triptolide; QU: Quercetin; Jak1: Janus kinase 1; Stat3: Signal transducer and activator of transcription 3; PI3K: Phosphoinositide 3-kinase; AKT: Protein kinase B; mTOR: Mammalian target of rapamycin.