Genetically influenced pediatric chronic pancreatitis: Radiologic perspectives

Table 3 Clinical, laboratory, and biochemical characteristics of patients according to gene groups

Variables	CFTR	CTRC/PRSS1	SPINK1	H value	P value
	Median (min-max)	Median (min-max)	Median (min-max)
Age (years)	13.00 (8-17)	16.00 (10-17)	11.50 (11-13)	3.270	0.195
Pancreatitis attacks (n)	4.00 (2-8)	3.00 (3-4)	4.00 (2-6)	1.749	0.417
Disease duration (years)	3.00 (1-7)	2.00 (1-3)	2.50 (1-3.5)	1.278	0.528
Serum amylase (U/L)	502.00 (133-2165)	1655.00 (790-3000)	1075.00 (480-1468)	5.303	0.071
Serum lipase (U/L)	1223.00 (133-2652)	1210.00 (703-1900)	700.00 (450-1614)	0.775	0.679
Total bilirubin (mg/dL)	0.40 (0.28-1.30)	0.70 (0.30-0.70)	0.70 (0.39-0.70)	1.412	0.494
Conjugated bilirubin (mg/dL)	0.12 (0.06-0.41)	0.30 (0.20-0.40)	0.30 (0.15-0.30)	4.198	0.123
ALP (U/L)	133.00 (116-433)	88.00 (65-206)	116.00 (84-130)	5.934	0.051
Serum calcium (mg/dL)	8.80 (8.6-9.2)	8.90 (8.5-9.3)	9.35 (9.1-9.4)	7.730	0.021a
Serum phosphorus (mg/dL)	3.90 (3.1-4.7)	4.00 (3.8-4.3)	4.00 (3.6-4.0)	0.356	0.837
PTH (pg/mL)	54.40 (38.4-74.0)	62.00 (62.0-62.0)	55.65 (49.3-66.2)	0.167	0.920
25(OH)D (ng/mL)	28.00 (14-35)	26.00 (22-41)	22.00 (22-22)	1.741	0.419
Serum triglycerides (mg/dL)	100.00 (90-104)	98.00 (85-110)	100.00 (85-110)	0.021	0.990
Total cholesterol (mg/dL)	162.50 (150-198)	172.50 (130-205)	180.00 (140-180)	0.040	0.980
IgG4 (mg/dL)	76.30 (34.6-115.8)	110.00 (63.0-110.0)	51.10 (44.2-58.0)	2.431	0.297

^aP < 0.05.

P values were calculated using the Kruskal-Wallis test. For variables available for a single patient in a group, minimum and maximum values coincide. min: Minimum; max: Maximum; ALP: Alkaline phosphatase; 25(OH)D: 25-Hydroxyvitamin D; IgG4: Immunoglobulin G4; PTH: Parathyroid hormone.