Red cell distribution width as a biomarker of disease activity in ulcerative colitis and Crohn’s disease

doi:10.3748/wjg.121569

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Oct 14, 2026; 32(38): 121569
Published online Oct 14, 2026. doi: 10.3748/wjg.121569

Table 2 Red cell distribution width and laboratory parameters across ulcerative colitis disease activity groups, median (interquartile range)

Variable	Remission (n = 110)	Mild (n = 75)	Moderate (n = 116)	Severe (n = 64)	P value
RDW-CV (%)	13.1 (12.7-13.7)	13.2 (12.8-13.9)	13.6 (13.0-14.8)	14.2 (13.4-16.0)	< 0.001
RDW-SD (fL)	41.5 (39.5-43.5)	41.2 (39.4-43.4)	42.1 (40.1-44.3)	42.8 (40.5-45.3)	0.32
CRP (mg/L)	1.2 (0.5-3.2)	2.4 (0.8-6.4)	6.7 (2.6-15.1)	11.8 (4.9-27.8)	< 0.001
Platelets	275 (230-324)	286 (239-342)	302 (254-357)	338 (276-396)	< 0.001

Disease activity was classified according to the ulcerative colitis endoscopic index of severity. RDW-CV: Red cell distribution width-coefficient of variation; RDW-SD: Red cell distribution width-standard deviation; CRP: C-reactive protein.

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Citation: Polat YH, Çakal B, Tece S, Yuksel I. Red cell distribution width as a biomarker of disease activity in ulcerative colitis and Crohn’s disease. World J Gastroenterol 2026; 32(38): 121569
URL: https://www.wjgnet.com/1007-9327/full/v32/i38/121569.htm
DOI: https://dx.doi.org/10.3748/wjg.121569

Polat YH, Çakal B, Tece S, Yuksel I. Red cell distribution width as a biomarker of disease activity in ulcerative colitis and Crohn’s disease. World J Gastroenterol 2026; 32(38): 121569 [DOI: 10.3748/wjg.121569]

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