Single-cell and bulk transcriptomics with machine learning decode B cell hub genes and diagnostic biomarkers in anal fistula

doi:10.3748/wjg.121425

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 32, Issue 38

This Article

(5)

(6)

(0)

(5)

(67)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Supplementary Materials of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Basic Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Oct 14, 2026; 32(38): 121425
Published online Oct 14, 2026. doi: 10.3748/wjg.121425

Full Size Figure Download Figure

Figure 11 CellChat analysis of SYK⁺ B cells in anal fistula. A: CellChat interaction network showing the number of interactions among different cell types. SYK⁺ B cells exhibit a markedly higher number of interactions compared to SYK^- B cells; B: Communication strength analysis reveals that SYK⁺ B cells possess significantly stronger interactions with surrounding immune and stromal cell populations; C: Outgoing and incoming signaling heatmaps demonstrate that SYK⁺ B cells show enhanced outgoing activity in key inflammatory and immune pathways; D: The ligand-receptor interactions between different cell types and SYK^+/- B cells.

Citation: Li TT, Li JN, Yang HW, Dou XY, Jiang L, Lai LX, Yu Q, Chen XY, Wang Y, Zhang XC, Ma HF, Song XB. Single-cell and bulk transcriptomics with machine learning decode B cell hub genes and diagnostic biomarkers in anal fistula. World J Gastroenterol 2026; 32(38): 121425
URL: https://www.wjgnet.com/1007-9327/full/v32/i38/121425.htm
DOI: https://dx.doi.org/10.3748/wjg.121425

Li TT, Li JN, Yang HW, Dou XY, Jiang L, Lai LX, Yu Q, Chen XY, Wang Y, Zhang XC, Ma HF, Song XB. Single-cell and bulk transcriptomics with machine learning decode B cell hub genes and diagnostic biomarkers in anal fistula. World J Gastroenterol 2026; 32(38): 121425 [DOI: 10.3748/wjg.121425]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.