Portulaca oleracea L.-derived exosome-like nanoparticles ameliorate colitis by modulating gut microbiota and metabolites to reduce endoplasmic reticulum stress

doi:10.3748/wjg.120885

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Oct 7, 2026; 32(37): 120885
Published online Oct 7, 2026. doi: 10.3748/wjg.120885

Table 1 Primer sequences

Gene		Primer sequences
Mus PERK	Forward	ACGGGACAAGTAGGGACCAA
Mus PERK	Reverse	CTGGGTGCTGAATGGGTAGA
Mus eIF2α	Forward	GCTCCACCCAGGTATGTGATG
Mus eIF2α	Reverse	TTTCTCTCTCCAGCCGTTCC
Mus Bip	Forward	GAACACTGTGGTACCCACCAAGAA
Mus Bip	Reverse	TCCAGTCAGATCAAATGTACCCAGA
Mus ATF4	Forward	GAAGAGGTCCGTAAGGCAAGG
Mus ATF4	Reverse	CAGCAAACACAGCAACACAAGA
Mus Occludin	Forward	AAGTGAATGGCAAGCGATCATA
Mus Occludin	Reverse	CTGTACCGAGGCTGCCTGAA
Mus Claudin-2	Forward	ACACTTGAGTCATCGCCCATC
Mus Claudin-2	Reverse	AATCCCAGGCAGAAGTTCACC
Mus Claudin-4	Forward	CGTCATCCGCGACTTCTACA
Mus Claudin-4	Reverse	GAGTAGGGCTTGTCGTTGCT
Mus ZO-1	Forward	TCCCACAAGGAGCCATTCCTG
Mus ZO-1	Reverse	GGGCTCAGCAGAGTTTCACCT
Mus β-actin	Forward	CATCCGTAAAGACCTCTATGCCAAC
Mus β-actin	Reverse	ATGGAGCCACCGATCCACA

Full Size Table

Citation: Liu XY, Liu ZX, Tan WW, Zhang WB, Qiao D, Chen SH, Zhang YL, Zheng L, Ge WS, Dai YC. Portulaca oleracea L.-derived exosome-like nanoparticles ameliorate colitis by modulating gut microbiota and metabolites to reduce endoplasmic reticulum stress. World J Gastroenterol 2026; 32(37): 120885
URL: https://www.wjgnet.com/1007-9327/full/v32/i37/120885.htm
DOI: https://dx.doi.org/10.3748/wjg.120885

Liu XY, Liu ZX, Tan WW, Zhang WB, Qiao D, Chen SH, Zhang YL, Zheng L, Ge WS, Dai YC. Portulaca oleracea L.-derived exosome-like nanoparticles ameliorate colitis by modulating gut microbiota and metabolites to reduce endoplasmic reticulum stress. World J Gastroenterol 2026; 32(37): 120885 [DOI: 10.3748/wjg.120885]

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