Efficacy of 7-day and 14-day potassium-competitive acid blocker-based bismuth-containing quadruple regimen for Helicobacter pylori infection

doi:10.3748/wjg.119668

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Oct 7, 2026; 32(37): 119668
Published online Oct 7, 2026. doi: 10.3748/wjg.119668

Table 2 Helicobacter pylori eradication rate according to the treatment group

Analysis	7-day PC-BMT	14-day PC-BMT	14-day P-BMT	7-day PC-BMT vs 14-day P-BMT		14-day PC-BMT vs 14-day P-BMT
Analysis	7-day PC-BMT	14-day PC-BMT	14-day P-BMT	Difference (95%CI)	P value	Difference (95%CI)	P value
ITT	76.5% (91/119)	78.8% (93/118)	77.8% (91/117)	-1.3% (-12.0 to 9.4)	0.111	1.0% (-9.5 to 11.6)	0.047
Modified ITT	80.5% (91/113)	83.8% (93/111)	80.5% (91/113)	0% (-10.3 to 10.3)	0.064	3.3% (-6.8 to 13.3)	0.014
Per-protocol	81.7% (89/109)	87.5% (91/104)	79.3% (84/106)	2.4% (-8.2 to 13.0)	0.027	8.3% (-1.8 to 18.3)	0.001

Non-inferiority margin of -8%. ITT: Intention-to-treat; P-BMT: Proton pump inhibitor-based bismuth-containing quadruple regimen; PC-BMT: Potassium-competitive acid blocker-based bismuth-containing quadruple regimen.

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Citation: Oh CK, Lim H, Noh JH, Gong EJ, Seo SI, Bang CS, Kim YJ, Shin WG, Kim JB, Jang HJ, Baik GH. Efficacy of 7-day and 14-day potassium-competitive acid blocker-based bismuth-containing quadruple regimen for Helicobacter pylori infection. World J Gastroenterol 2026; 32(37): 119668
URL: https://www.wjgnet.com/1007-9327/full/v32/i37/119668.htm
DOI: https://dx.doi.org/10.3748/wjg.119668

Oh CK, Lim H, Noh JH, Gong EJ, Seo SI, Bang CS, Kim YJ, Shin WG, Kim JB, Jang HJ, Baik GH. Efficacy of 7-day and 14-day potassium-competitive acid blocker-based bismuth-containing quadruple regimen for Helicobacter pylori infection. World J Gastroenterol 2026; 32(37): 119668 [DOI: 10.3748/wjg.119668]

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