Low-dose vs standard-dose minocycline in bismuth quadruple therapy for first-line Helicobacter pylori eradication: A randomized controlled, noninferiority trial

doi:10.3748/wjg.122851

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Randomized Clinical Trial

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Sep 28, 2026; 32(36): 122851
Published online Sep 28, 2026. doi: 10.3748/wjg.122851

Table 4 Ulcer healing rates between the two groups

Group	Ulcer healing status				Healing rates (%)
Group	Complete healing	Marked healing	Partial healing	Non- healing	Healing rates (%)
Low-dose group	9	8	5	3	88.0
Standard-dose group	10	8	5	4	85.2
P value	1.000

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Citation: Zhu YN, Wang YB, Li L, Ren YD, Wang RR, Ji YL, Wang YP, Zhai HY, Jiang Y. Low-dose vs standard-dose minocycline in bismuth quadruple therapy for first-line Helicobacter pylori eradication: A randomized controlled, noninferiority trial. World J Gastroenterol 2026; 32(36): 122851
URL: https://www.wjgnet.com/1007-9327/full/v32/i36/122851.htm
DOI: https://dx.doi.org/10.3748/wjg.122851

Zhu YN, Wang YB, Li L, Ren YD, Wang RR, Ji YL, Wang YP, Zhai HY, Jiang Y. Low-dose vs standard-dose minocycline in bismuth quadruple therapy for first-line Helicobacter pylori eradication: A randomized controlled, noninferiority trial. World J Gastroenterol 2026; 32(36): 122851 [DOI: 10.3748/wjg.122851]

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