Anti-glutamic acid decarboxylase autoimmunity presenting as chronic intestinal pseudo-obstruction with dysautonomia and late-onset autoimmune diabetes: A case report

doi:10.3748/wjg.120568

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Report

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Sep 28, 2026; 32(36): 120568
Published online Sep 28, 2026. doi: 10.3748/wjg.120568

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Figure 4 Treatment timeline. Timeline illustrating the clinical course and therapeutic interventions, including initial presentation with obstructive symptoms, partial response to prokinetic therapy, marked improvement following corticosteroids and intravenous immunoglobulins, subsequent relapse, and sustained remission after treatment with intravenous methylprednisolone, intravenous immunoglobulins, and rituximab. IVIG: Intravenous immunoglobulins; IVMP: Intravenous methylprednisolone.

Citation: Kharief M, O’Byrne R, William K, Hasabarsoul MA, Tuohy O, Morcos A. Anti-glutamic acid decarboxylase autoimmunity presenting as chronic intestinal pseudo-obstruction with dysautonomia and late-onset autoimmune diabetes: A case report. World J Gastroenterol 2026; 32(36): 120568
URL: https://www.wjgnet.com/1007-9327/full/v32/i36/120568.htm
DOI: https://dx.doi.org/10.3748/wjg.120568

Kharief M, O’Byrne R, William K, Hasabarsoul MA, Tuohy O, Morcos A. Anti-glutamic acid decarboxylase autoimmunity presenting as chronic intestinal pseudo-obstruction with dysautonomia and late-onset autoimmune diabetes: A case report. World J Gastroenterol 2026; 32(36): 120568 [DOI: 10.3748/wjg.120568]

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