Anti-glutamic acid decarboxylase autoimmunity presenting as chronic intestinal pseudo-obstruction with dysautonomia and late-onset autoimmune diabetes: A case report

doi:10.3748/wjg.120568

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Report

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Sep 28, 2026; 32(36): 120568
Published online Sep 28, 2026. doi: 10.3748/wjg.120568

Table 2 Anti-glutamic acid decarboxylase antibody levels

Antibodies	April 2023	August 2023	March 2024	March 2025
Anti-GAD antibodies (IU/mL)	255	44.0	16.0	9.0
Anti-neutrophil antibodies	Negative	Not tested	Not tested	Not tested

Anti-GAD: Anti-glutamic acid decarboxylase.

Full Size Table

Citation: Kharief M, O’Byrne R, William K, Hasabarsoul MA, Tuohy O, Morcos A. Anti-glutamic acid decarboxylase autoimmunity presenting as chronic intestinal pseudo-obstruction with dysautonomia and late-onset autoimmune diabetes: A case report. World J Gastroenterol 2026; 32(36): 120568
URL: https://www.wjgnet.com/1007-9327/full/v32/i36/120568.htm
DOI: https://dx.doi.org/10.3748/wjg.120568

Kharief M, O’Byrne R, William K, Hasabarsoul MA, Tuohy O, Morcos A. Anti-glutamic acid decarboxylase autoimmunity presenting as chronic intestinal pseudo-obstruction with dysautonomia and late-onset autoimmune diabetes: A case report. World J Gastroenterol 2026; 32(36): 120568 [DOI: 10.3748/wjg.120568]

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